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chelating and medical interest

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الكلية كلية طب الاسنان     القسم  العلوم الاساسية     المرحلة 1
أستاذ المادة نجلاء ناصر حسين هادي       21/11/2018 07:56:29
Chelating and medical interest
Chelating agent:
organic chemicals that form coordination bonds with a central metal ion, used to chemically remove ions from solutions, medicinally against microorganisms, to treat metal poisoning and in chemotherapy protocols.
Dental agent:
biologically active substance intended for use in diagnosis, treatment, or prevention of oral disease or other oral abnormalities.
Dental caries inhibitor:
any substance or agent which suppresses or prevents the development of dental cavities or caries.
Drug/agent:
biologically active substance, including those intended for use in diagnosis, treatment, or prevention of disease or other abnormalities, for the relief of suffering, or control or improvement of a physical or mental state; includes biological products.
Chelation Therapy:
Chelation is a chemical process that has applications in many areas,
including medical treatment, environmental site rehabilitation, water purification, and so forth. In the medical environment, Chelation is used to treat cardiovascular disease, heavy metal toxicity, and to remove metals that accumulate in body tissues because of genetic disorders (hemochromatosis).
This protocol will address the use of Chelation therapy for the
removal of heavy metals as a result of ingested or environmental
exposure.
Chelation therapy, simply defined, is the process by which a molecule encircles and binds (attaches) to the metal and removes it from tissue. Depending on the drug used, chelating agents specific to the heavy metal involved are given orally, intramuscularly, or intravenously. Once the bound metal leaves the tissue, it enters the bloodstream, is filtered from the blood in the kidneys, and then is eliminated in the urine. The decision to chelate should be made only by professionals with experience using chelation therapy, preferably in consultation with a poison control center or a medical toxicologist.

How does Chelation work to improve health?
Chelation Therapy, along with nutrition, promotes health by
correcting the major underlying cause of arterial blockage and
heart disease. Damaging oxygen free radicals are increased in the presence of such metals as iron, lead, and aluminum, and are
believed to act as a chronic irritant to blood vessel walls and cell
membranes. (EDTA) Chelation Therapy and other agents remove the heavy metals, thus decreasing the oxidant burden on the body and increasing its antioxidant reserves. Other risk factors for heart disease including high homocysteine and insulin levels are also addressed. This combined approach utilizing nutrition and Chelation Therapy has helped many people rid themselves of angina pains and prevent further arterial blockages.
The following table summarizes chelating agents, the heavy
metals they are used to treat, their route of administration, and
their brand name.
Chelating Agent Toxin Drug
Dimercaprol (BAL) Arsenic
Lead
Mercury
(inorganic) Dimercaptol
Injection
B.P.
BAL in Oil
Dimercaptosiccinic
acid (DMSA)
(Succimer) Arsenic
Lead
Mercury Chemet
Dimer capto propane sulfonate
(DMPS) Arsenic Bulk form for
compounding
by pharmacists
D-pencil amine Arsenic
Mercury
Lead Metalcaptase
Pencil amine
Cuprimine
Deepen
Ethylene diamin tetra- acetic
acid (EDTA)
(Edetate disodium) Lead Cheal amide
Versenate

Chelation can be accomplished with nutrients that protect our
bodies from heavy metals.
1- Magnesium protects us from aluminum
2- Amino acids, calcium, iodine, selenium, vitamin C, and zinc protest us from arsenic.
3- Amino acids, calcium, vitamin C and zinc protect us from
cadmium.
4- Amino acids, calcium, iron, Vitamin C, vitamin e, and zinc
protect us from lead.
5- Amino acids, pectin selenium, and vitamin C protect us
from mercury.
6- Vitamin C, molybdenum and sulfur-containing amino acids(cysteine and tyrosine) chelate copper.


المادة المعروضة اعلاه هي مدخل الى المحاضرة المرفوعة بواسطة استاذ(ة) المادة . وقد تبدو لك غير متكاملة . حيث يضع استاذ المادة في بعض الاحيان فقط الجزء الاول من المحاضرة من اجل الاطلاع على ما ستقوم بتحميله لاحقا . في نظام التعليم الالكتروني نوفر هذه الخدمة لكي نبقيك على اطلاع حول محتوى الملف الذي ستقوم بتحميله .
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